Takai, M/ Uehara, Y/ Beisler, JA 1979: Usnic acid derivatives as potential antineoplastic agents. - Journal of Medicinal Chemistry22: 1380-1384. [RLL List # 106-90 / Rec.# 18198] Keywords: USNIC/ CARCINOMA/ TUMOR/ MEDICINE
Abstract: 1 figure. 2 tables. Several formulas. ["Usnic acid, a lichen antibiotic, showed low-level activity in the Lewis lung carcinoma test system." Several synthetic derivatives were prepared. However, "...no significant increases in survival of test animals over controls were shown by any of the synthetic compounds in the P388 or the Lewis lung carcinoma test systems."]
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