M. Bačkorová, M. Bačkor, J. Mikeš, R. Jendželovský and P. Fedoročko 2011: Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid. - Toxicology in Vitro25(1): 37-44. [RLL List # 221 / Rec.# 32334] Keywords: CANCER CELL/ CELL CYCLE/ CYTOTOXICITY/ LICHEN METABOLITES/ MEDICINE/ SECONDARY CHEMISTRY/ PARIETIN/ ATRANORIN/ USNIC ACID/ GYROPHORIC ACID
Abstract: [Tests on nine human cancer cell lines. "However, in comparison with parietin and gyrophoric acid, the suppression of viability and cell proliferation by usnic acid or atranorin was found to be more efficient at equitoxic doses and correlated more strongly with an increased number of floating cells or a higher apoptotic index. This study has confirmed a differential sensitivity of cancer cell lines to lichen secondary metabolites."]